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Resistant Bacteria! or False Positive Breath Tests

Breath tests are the most accurate way of detecting H.pylori without actually having an endoscopy (stomach examination). Breath tests are especially useful after treatment to make sure H.pylori is cured. Urea breath tests are known to be completely harmless. Either C14-urea or C13-urea tests are used. Read about them at the diagnosis section at http://www.helico.com/diag_breath.html where a diagram can be found. C14-urea breath tests use a radioactive tracer but such a tiny amount that it can be used safely at any age. It is a 15 minute test, convenient and inexpensive. The C13-urea test uses a stable isotope of carbon which is also harmless but requires two breath samples and takes about 30 minutes. Both tests have accuracy greater than 90%.

Moderators: barjammar, Toni

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Brewer
Posts: 1
Joined: Sun Mar 07, 2010 11:46 am

Resistant Bacteria! or False Positive Breath Tests

Post by Brewer »

I was diagnosed with Hpylori 3 years ago and to this date I have not had any success in killing the bacteria!!


My specialist has given up on me as we have tried every medication known to get rid of it and it wont go away!


I have had readings as low as 100 (breath test) but it soon rises back to anywhere between 400 - 1000! why is the bacteria so resistant in my stomach?? it must like it in there... I had a tube put down to see what was going on and no signs of an ulcer and biopsy from 1 area was negative but still hiding in there somewhere...


Can you suggest anything else I can try its getting quiet depressing! my mother and sisters had it and it went away with first treatment!! I have tried it all including Denol and tetracycline.

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barjammar
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Location: Perth Australia
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Re: Resistant Bacteria! or False Positive Breath Tests

Post by barjammar »

Can you list your treatments and follow-up tests in a readable format for me (see below)?
If you had a biopsy without bacteria being seen then it suggests that the bacteria may be eradicated already and the breath test is a false positive result. That could occur if you were taking acid blockers prior to the test or you had some bacteria in the stomach and oesophagus which were not Helicobacter, but were from the mouth. This can occur sometimes if there is low stomach acidity (autoimmune atrophic gastritis perhaps) or delayed gastric emptying and a stomach which contains food at the time of the test. So you need another breath test carefully done 7 days after stopping all acid blocker treatment and then also have a serology blood test for helicobacter and a stool test for Helicobacter antigen.
In the meantime, if you want to list the dates of treatments and test and the results it might help work this out. Use the format below:
2009/08/22, treament, amoxi 3g/day, omeprazole 40 mg/day, metronidazole 1.5g/day, for 2 weeks
2009/09/26, urea breath test, 345 dpm
etc.
Also, have a read of the article we have on line for you (see treatment section). There are other options we can use.
8-)
Check the link below for information on hard-to-treat cases. Then search the forums for questions and answers similar to yours.
docs/200808%20stenstrom%20Hp%20Treatment.pdf

adepts
Posts: 1
Joined: Sun Apr 25, 2010 4:34 pm

Re:numbers of hp on breath test

Post by adepts »

hi i am breath tested positive with hp 3011 in number.
after a week my wife also received positive testing with 1800 numbers lot more than 200.

what are significance in term of numbers and its possible consequences. Luckly my two sons are negative.

Regards

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barjammar
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Joined: Fri Feb 05, 2010 11:10 am
Location: Perth Australia
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Re: Resistant Bacteria! or False Positive Breath Tests

Post by barjammar »

I can't dwell on this as I have other things to do. However, it does not make any difference whether you have 500 or 1500 on the breath test. The level of bacteria does not predict what the outcome is, although my impression is that duodenal ulcer patients have more bacteria and more breath counts.
You will have to find a doctor who specialises in Helicobacter. I can't understand why the biopsy was negative and only one biopsy was taken. Keep reading the web site FAQ and see what turns up. :geek:
Check the link below for information on hard-to-treat cases. Then search the forums for questions and answers similar to yours.
docs/200808%20stenstrom%20Hp%20Treatment.pdf

Helico_expert
Site Admin
Posts: 3639
Joined: Wed Mar 02, 2011 7:20 am

Re: Resistant Bacteria! or False Positive Breath Tests

Post by Helico_expert »

Hi,

more than half of the world population is infected by H. pylori. only a very very small percentage of people will get stomach cancer. Among the infected, most of them remain asymptomatic and remain healthy. So, dont have to be too worry about it.

It is possible to remove the bacteria permanently. Just have to find the right combination of antibiotics. Seek second or third opinion from your local doctor. One of them should have a treatment plan that will cure your son.

Tobiasgar
Posts: 5
Joined: Fri Aug 26, 2011 1:44 pm

Re: Resistant Bacteria! or False Positive Breath Tests

Post by Tobiasgar »

While Helicobacter pylori eradication therapy has been established as a step in preventing gastric cancer and peptic ulcers, a new study suggests that H. pylori eradication post gastric resection might prevent the development of cancer following surgery.
In an Italian prospective study Screening of Helicobacter pylori Infection After Gastrectomy for Cancer or Peptic Ulcer published in Archives of Surgery, researchers looked at 187 patients with previous gastric resection for the presence of precancerous lesions in the gastric stump.
The researchers found that those patients undergoing gastric resection for cancer with an active H. pylori infection are more likely to have precancerous lesions than patients negative for H. pylori in the same diagnostic group. Likewise, H. pylori-positive patients undergoing surgery for cancer have a higher risk of lesions than patients undergoing resection surgery.

The researchers conclude that eradication for H. pylori might prevent gastric cancer developing after gastric resection surgery.

sunshine37
Posts: 35
Joined: Sun Jun 07, 2015 7:34 am
Location: United States

Re: Resistant Bacteria! or False Positive Breath Tests

Post by sunshine37 »

barjammar wrote:Can you list your treatments and follow-up tests in a readable format for me (see below)?
If you had a biopsy without bacteria being seen then it suggests that the bacteria may be eradicated already and the breath test is a false positive result. That could occur if you were taking acid blockers prior to the test or you had some bacteria in the stomach and oesophagus which were not Helicobacter, but were from the mouth. This can occur sometimes if there is low stomach acidity (autoimmune atrophic gastritis perhaps) or delayed gastric emptying and a stomach which contains food at the time of the test. So you need another breath test carefully done 7 days after stopping all acid blocker treatment and then also have a serology blood test for helicobacter and a stool test for Helicobacter antigen.
In the meantime, if you want to list the dates of treatments and test and the results it might help work this out. Use the format below:
2009/08/22, treament, amoxi 3g/day, omeprazole 40 mg/day, metronidazole 1.5g/day, for 2 weeks
2009/09/26, urea breath test, 345 dpm
etc.
Also, have a read of the article we have on line for you (see treatment section). There are other options we can use.
8-)
hello:

my boyfriend tested negative for H Pylori both in his blood test (IgG) and urea breath test. he is taking a stool antigen test to be sure. he wants me to take the urea breath test, too. i have had the tests below, already.

stool test negative June29 2015 (was off Nexium 10 days prior to test-was not taking anything else...still am not).
stool test negative may28 2015 (had been taking Nexium at that time).
IgM antibody test positive 2.2 (1.1 minimum to show probable infection).

i read above that the urea breath test can show a false positive if there is food in the stomach or low acid in the stomach or other bacteria in the stomach/esophagus from the mouth.
prior to the test, i read on the testing website that you only have to had fasted for one hour. is that correct?
how can i make sure that i don't get a false positive? how long should I fast prior to the test to be sure... i read that one hour fasting is enough, but saw that overnight fasting is used, too. (http://www.rah.sa.gov.au/nucmed/urea/urea_docguide.htm)
i think that i must have enough acid in my stomach, as i get at least a little bit of heartburn daily, which i am trying to keep at a minimum, to prevent it from becoming acid relux. however, sometimes, i have read, that you can get heartburn from having too little acid.

Maybe I should get an IgG or IgA antibody test prior to the breath test to see whether or not I actually have antibodies? (as my doctor chose the IgM test, which is not the usual). (I just read that serology tests are only 50% effective to show infection in populations where the HP is less than 20%, such as US... Also, read that the IgG test is not as used now, due to concerns about its accuracy. http://www.bcbsms.com/com/bcbsms/apps/P ... ylori.html Due to the problems with accuracy of blood tests, is it possible to have a false positive antibody/serology blood test? Or, would it more likely show a false negative?

thank you...

best wishes,

Sunshine

Helico_expert
Site Admin
Posts: 3639
Joined: Wed Mar 02, 2011 7:20 am

Re: Resistant Bacteria! or False Positive Breath Tests

Post by Helico_expert »

breath test can give false negative if your stomach is not acid enough. The food in your stomach may make your stomach slightly less acidic. So you should wait for at least 1 to 2 hrs for the food to pass your stomach. Best is fasting overnight. So you feel a bit hungry, and for sure you'll have acid in your stomach.

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