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Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?

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2 members of same family with h-pylori

After many years of H.pylori infection a cancer can develop in the stomach. This is particularly common in Latin America and Asia (esp. Japan). It is believed that lifelong inflammation of the stomach lining causes low acidity which then allows carcinogens to be active in the stomach. These then cause stem cells (part of the healing process) to mutate and become cancer cells.

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lynxgal
Posts: 1
Joined: Tue Jul 06, 2010 7:43 pm

2 members of same family with h-pylori

Post by lynxgal »

I was diagnosed with H-pylori about 11 years ago when it was discovered I had an ulcer. At the time I was treated with the antibiotics. 2 years later my father was told he had H-pylori and was diagnosed with stomach cancer. My grandfather died a few years ago and at that time they were pretty certain he had stomach cancer however he declined the testing so it was only speculation.

I am now experiencing almost the same symptoms I had 11 years ago. What are the chances that the h-pylori has become active again after 11 years? Should I be asking for my doctor to look at my stomach due to the family history of h-pylori and stomach cancer.

mrsh1968
Posts: 3
Joined: Fri Aug 20, 2010 2:57 am

Re: 2 members of same family with h-pylori

Post by mrsh1968 »

I think if you have the same symptoms then it would be wise to get re-tested and if necessary treated.

Rex
Posts: 3
Joined: Fri Jan 07, 2011 3:55 pm

Re: 2 members of same family with h-pylori

Post by Rex »

this is a very dangerous disease, pylori is detected in patients with a peptic ulcer, the normal procedure is to eradicate it and allow the ulcer to heal. The standard first-line therapy is a one week "triple therapy" consisting of proton pump inhibitors such as omeprazole, lansoprazole and the antibiotics clarithromycin and amoxicillin.

web Designers
Posts: 1
Joined: Thu Mar 22, 2018 1:21 pm

Re: 2 members of same family with h-pylori

Post by web Designers »

Almost half of the world’s population is infected with H pylori. The incidence of infection has been reported to be as high as 80% in less developed countries and as low as 20% in Western countries. H pylori is involved in the etiology of gastric mucosa-associated lymphoid tissue (MALT)lymphoma and gastric adenocarcinoma, leading the World Health Organization to declare H pylori a first degree carcinogen. Less invasive diagnostic methods have enabled easier and earlier diagnosis and more widespread use of treatments.

Although H pylori infection is thought to occur in childhood, its method of transmission is not known. Research in highly infected populations has shown the importance of intra-familial infections, bad hygiene and lower socio-economical status in the spread of H pylori. However, these routes suggest infection is preventable.

The total time to exposure to H pylori has been found to correlate with the development of gastric adenocarcinoma, making diagnosis and eradication of the bacteria crucial. Furthermore, re-infection with H pylori may occur after eradication, owing to exposure to untreated individuals, indicating treatment focused on the patient alone will not result in total eradication. We sought to determine whether treatment of H pylori should be extended to H pylori-positive family members dwelling with the patient, or whether treatment of the patient alone would be sufficient. Treatment extended to the family would theoretically decrease the risk of re-infection.

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