Only registered users are allowed to post. To register, please click here

Should you have any problem in posting, registering, or login, please do not hesitate to contact the admin at Marshall.centre(at)gmail(dot)com. In the subject, please use "Help needed for www.helico.com"

Advertisement is not allowed. While we encourage discussion, please try not to promote your website, goods, or unproven treatment here.

This is a non-profit website. We will try our best to help anyone that has question about H. pylori and their treatment. We shall provide the most accurate answer about H. pylori. You can help us by clicking here to keep this forum alive.

Some useful guides
How to post in the forum?
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?

If you are confirmed with H. pylori, in your convenient time, please help us with the symptoms survey that you are experiencing.
Symptoms survey
(contributed by frostyfeet)


此网站免费然您阅读。若想分享心得或提问,请先注册
若有困难注册,请联络站长 Marshall.centre(at)gmail(dot)com。标题请用 "Help needed for www.helico.com"
此网站不允许打广告。我们欢迎任何的讨论。但尽量不要推销没医学根据的网站,商品或治疗方案。
此网站是非盈利网站。我们会尽最大能力提供任何有关幽门螺杆菌的讯息。您的捐款可以让我们继续帮助更多的病人。

指南
如何贴文?
欧洲幽门螺杆菌治疗共识 5
第五次全国幽门螺杆菌感染处理共识报告
用药后,多久以后可以再做吹气测试?

Gastric cancer and Hp genomics internal project

One of the first bugs to be sequenced, H.pylori has a small genome (1.6 MD) befitting its lifestyle in a hostile acidic mucosal niche. Of the 1500 genes, 750-1000 are essential, the others are different in each strain. Hp has an "open pan-Genome" which means the more strains you look at the more genes you will find - i.e. you will never have a complete set of all its possible genes!

Moderators: Toni, barjammar, stomach

Post Reply
stomach
Posts: 3
Joined: Tue Feb 23, 2010 11:32 am

Gastric cancer and Hp genomics internal project

Post by stomach »

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

Hopefully, this new tech can help us to understand how much Hp has involved in gastric cancer!

rocky123
Posts: 1
Joined: Wed Aug 01, 2012 7:25 pm

Re: Gastric cancer and Hp genomics internal project

Post by rocky123 »

The focus of the laboratory will be on the bacterial pathogen Helicobacter pylori and its role in the induction of gastric malignancies. H. pylori is a highly successful bacterial pathogen that infects and is perfectly adapted to the human stomach. Despite a dramatic decline of infection rates in the developed world in the past 3-4 decades, it still colonizes roughly half of the world’s population.
rocky

indancesky
Posts: 3
Joined: Thu Aug 02, 2012 11:19 am

Re: Gastric cancer and Hp genomics internal project

Post by indancesky »

Despite a dramatic decline of infection rates in the developed world in the past 3-4 decades, it still colonizes roughly half of the world’s population.

Helico_expert
Site Admin
Posts: 3797
Joined: Wed Mar 02, 2011 7:20 am

Re: Gastric cancer and Hp genomics internal project

Post by Helico_expert »

Despite a dramatic decline of infection rates in the developed world in the past 3-4 decades, it still colonizes roughly half of the world’s population.
this statement is half true. infection rate in developed world is less than 20%.

stomach
Posts: 3
Joined: Tue Feb 23, 2010 11:32 am

Re: Gastric cancer and Hp genomics internal project

Post by stomach »

Helico_expert wrote:
Despite a dramatic decline of infection rates in the developed world in the past 3-4 decades, it still colonizes roughly half of the world’s population.
this statement is half true. infection rate in developed world is less than 20%.

So let's have a look at the genomic data that ICGC has sequenced (http://www.icgc.org/icgc/cgp/69/509/70268). I guess it will tell us more exciting stories of gastric cancer....

fruitlover
Posts: 5
Joined: Fri Aug 10, 2012 3:30 pm
Location: USA
Contact:

Re: Gastric cancer and Hp genomics internal project

Post by fruitlover »

Wow, great info! Yes hopefully, this new tech can help us to understand more about Hp genomics and gastric cancer. Thanks for sharing!

broken850
Posts: 1
Joined: Mon Oct 01, 2012 2:27 pm

Re: Gastric cancer and Hp genomics internal project

Post by broken850 »

I want to get my parents well water tested as soon as possible. I'm not really sure where to start or who to contact. Would someone from Penn State be interested or be able to test our well?
angel

Helico_expert
Site Admin
Posts: 3797
Joined: Wed Mar 02, 2011 7:20 am

Re: Gastric cancer and Hp genomics internal project

Post by Helico_expert »

where is your parents' well? In United State? I think it's very difficult for the well water to be contaminated with H. pylori. Other organism maybe. But not H. pylori.

Helico_expert
Site Admin
Posts: 3797
Joined: Wed Mar 02, 2011 7:20 am

Re: Gastric cancer and Hp genomics internal project

Post by Helico_expert »

you can take the lansoprazole to control your gastric. then take the other two antibiotics plus lansoprazole when you come back after 3 weeks.

Post Reply

Return to “Genomics of Helicobacters”