PPI in Triple Therapy: Questions about timing
Posted: Mon Feb 25, 2019 5:39 am
Hi:
I'm about to begin triple therapy for H.Pylori: Amoxicillin, Clarithromycin+ PPI (Omeprazole 40 mg)
As prescribed by Gastroenterologist, the PPI is: Omeprazole one tablet 40 mg once daily for 14 days. One hour before meals
When I asked pharmacist to clarify timing of PPI in relation to antibiotics, she said the PPI must be taken very first thing in the morning, even before morning coffee. At least hour before eating anything or taking any medication. Personally, it would be more convenient for me to take it an hour before evening meal..
She was also surprised the PPI wasnt prescribed for twice a day-- but only once daily. So some divergence here from whats on the prescription
Two questions:
1) Can the PPI simply be taken one hour (or more) before evening meal and evening antibiotics, as the prescription implies?
2) Is one 40 mg capsule Omeprazole- once daily- reasonable as part of triple therapy regime? Or might it have been an error and actually that should have been split in two doses?
Thanks
I'm about to begin triple therapy for H.Pylori: Amoxicillin, Clarithromycin+ PPI (Omeprazole 40 mg)
As prescribed by Gastroenterologist, the PPI is: Omeprazole one tablet 40 mg once daily for 14 days. One hour before meals
When I asked pharmacist to clarify timing of PPI in relation to antibiotics, she said the PPI must be taken very first thing in the morning, even before morning coffee. At least hour before eating anything or taking any medication. Personally, it would be more convenient for me to take it an hour before evening meal..
She was also surprised the PPI wasnt prescribed for twice a day-- but only once daily. So some divergence here from whats on the prescription
Two questions:
1) Can the PPI simply be taken one hour (or more) before evening meal and evening antibiotics, as the prescription implies?
2) Is one 40 mg capsule Omeprazole- once daily- reasonable as part of triple therapy regime? Or might it have been an error and actually that should have been split in two doses?
Thanks