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For how long to take PPI after finishing antibiotic

The most popular treatments consist of two antibiotics (one of which is usually clarithromycin) plus a strong acid blocker such as omeprazole (PriLosec, Nexium, Somac, Zoton, etc.). Treatment is for 7-10 days. Cure rate is about 85%

Moderators: Toni, barjammar, luci2010, Ondek-Expert, kkimura

Helico_expert
Site Admin
Posts: 4102
Joined: Wed Mar 02, 2011 7:20 am

Re: For how long to take PPI after finishing antibiotic

Post by Helico_expert »

I am not familiar with UK system. But you can check this online chemist
https://www.expresschemist.co.uk/produc ... o-12x.html

AMERC
Posts: 42
Joined: Mon Dec 07, 2020 5:23 am

Re: For how long to take PPI after finishing antibiotic

Post by AMERC »

Thanks but not available in the UK

Can I do the blood test for h pylori whilst on omeprazole 20mg or could it give me a false negative or positive.

This just you confirm that I had it rather than if it has been eradicated

Helico_expert
Site Admin
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Joined: Wed Mar 02, 2011 7:20 am

Re: For how long to take PPI after finishing antibiotic

Post by Helico_expert »

you can do multiple blood tests and see the level of antibody against HP. If the concentration is stable every 3 months, then you are still infected. If the concentration gradually reduce every 3 months, then you are free of H. pylori.

AMERC
Posts: 42
Joined: Mon Dec 07, 2020 5:23 am

Re: For how long to take PPI after finishing antibiotic

Post by AMERC »

Can the symptoms get worse after the eradication therapy which what seems to have happened in my case.

Helico_expert
Site Admin
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Joined: Wed Mar 02, 2011 7:20 am

Re: For how long to take PPI after finishing antibiotic

Post by Helico_expert »

Usually when after HP eradication (for real), then the inflammation will slowly go away and the condition will improve.

Sometimes, the stomach is trying to readjust to a new environment where there is no H. pylori, the symptoms (such as reflux) will temporarily got worse and then improve.

AMERC
Posts: 42
Joined: Mon Dec 07, 2020 5:23 am

Re: For how long to take PPI after finishing antibiotic

Post by AMERC »

Helico_expert wrote:
Thu Dec 17, 2020 9:15 am
you can do multiple blood tests and see the level of antibody against HP. If the concentration is stable every 3 months, then you are still infected. If the concentration gradually reduce every 3 months, then you are free of H. pylori.
Thanks. Just to confirm that being on ppi should not affect the blood test results

Helico_expert
Site Admin
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Joined: Wed Mar 02, 2011 7:20 am

Re: For how long to take PPI after finishing antibiotic

Post by Helico_expert »

PPI will not affect blood test result

AMERC
Posts: 42
Joined: Mon Dec 07, 2020 5:23 am

Re: For how long to take PPI after finishing antibiotic

Post by AMERC »

Helico_expert wrote:
Fri Dec 18, 2020 8:13 am
Usually when after HP eradication (for real), then the inflammation will slowly go away and the condition will improve.

Sometimes, the stomach is trying to readjust to a new environment where there is no H. pylori, the symptoms (such as reflux) will temporarily got worse and then improve.
Thank you Helico Expert

Typically how long does this readjustment takes. I am into my 8th week after finishing the triple therapy treatment. The acidity symptoms are still ongoing some days more than others. Trying to control it with omeprazole 20mg daily.

My acidity started in June but with omeprazole had gradually bought under control such that I was of ppi for 12 days before endoscopy in October sometime unthinkable now. Post therapy treatment things seems to have gone really backwards

Is it possible for h pylori to cause over acid production but not cause any gastritis or inflammation? Have you come across such cases,?

Helico_expert
Site Admin
Posts: 4102
Joined: Wed Mar 02, 2011 7:20 am

Re: For how long to take PPI after finishing antibiotic

Post by Helico_expert »

a very good question. We have not seen a case where H. pylori does not cause inflammation. But perhaps we have not examine healthy people to see if their H. pylori causes inflammation. In almost every case, only symptomatic people seek medication examination. Hence all of them has inflammation.

How long will it take to recover? that's depending on the damage done. The younger you are, the higher chance of you have early recovery.
Some damage can be permanent and may never recover. But, with H. pylori eradicated, we believe your gastric cancer risk will not continue to rise

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